Zinc absorption in the rat
نویسندگان
چکیده
منابع مشابه
Studies on the absorption of zinc by rat intestine.
1. A technique is described for the measurement of the extent of 65Zn absorption by different regions of the intestine in the intact rat. Using this technique it was shown that the duodenum contributed 60%, the ileum 30% and the jejunum 10% to the over-all absorption of 65Zn. Negligible absorption of 65Zn occurred from the caecum and colon. 2. Using ligated loops of rat duodenum in situ, 65Zn a...
متن کاملINTESTINAL ZINC ABSORPTION IN DESFERROXAMINE-TREATED RATS
Desferroxamine (Desferal) is used tochelate iron in thalassemia, a disease of very high prevalence in various parts of lran. We have investigated intestinal zinc absorption in Desferal-treated rats which, in pilot experiments, showed low serum levels of both iron and zinc. Intraperitoneal administration of ten 0.5 g doses of Desferal (one injection every other day) to male rats produced sev...
متن کاملZinc Pyrithione in the Rat*
-The pharmacoklnetic profile of orally administered [2,6-t4C'l-labelled zinc pyrithione (ZPT) was defined in male and female rats and was used to predict the blood concentrations of t4C at steady state correlating with the skeletal-muscle weakness observed in long-term feeding tests and mechanism studies. The t*C concentration was determined in blood, urine and faeces as a function of time foll...
متن کاملZinc absorption adapts to zinc supplementation in postmenopausal women.
OBJECTIVE To determine if human Zn absorption adapts to chronic high Zn intakes. METHODS Zn absorption was measured at 0, 8, and 16 wk in healthy postmenopausal women who consumed controlled diets with approximately 5 mg Zn from food, supplemented to 14 (n = 6), 32 (n = 3), or 47 (n = 3) mg Zn/d for 22 wk. Zn absorption for 1 day was determined by (65)Zn-labeling of meals and whole body scint...
متن کاملInvestigation of Intestinal Absorption of Pyridinones in Rat
Recently, it has been shown that a number of hydroxypyridinones such as 1,2-dimethyl-3-hydroxypyridin-4-one (L1) are useful for the treatment of iron overload in place of desferrioxamine in thalassaemic patients. In this study, the intestinal absorption (I.A.) of L1 and one of its analogues namely 2-methy-3-hydroxypyridin-4-one (L2), which possesses a higher partition coefficient (Kpart) than L...
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ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 1981
ISSN: 0007-1145,1475-2662
DOI: 10.1079/bjn19810005